diff --git a/.changeset/dvorak-shortcut-logical-key.md b/.changeset/dvorak-shortcut-logical-key.md
new file mode 100644
index 000000000..ddbf72db0
--- /dev/null
+++ b/.changeset/dvorak-shortcut-logical-key.md
@@ -0,0 +1,5 @@
+---
+"gitbook": patch
+---
+
+Match keyboard shortcuts by the logical character typed instead of the physical key position, so that ⌘-C no longer opens the Assistant on the Dvorak layout (and other non-QWERTY layouts).
diff --git a/packages/gitbook/src/components/AIChat/AIChatInput.tsx b/packages/gitbook/src/components/AIChat/AIChatInput.tsx
index a396ea1f6..4e7b8c49d 100644
--- a/packages/gitbook/src/components/AIChat/AIChatInput.tsx
+++ b/packages/gitbook/src/components/AIChat/AIChatInput.tsx
@@ -51,6 +51,9 @@ export function AIChatInput(props: {
         },
         {
             enableOnFormTags: true,
+            // Match the logical character so Dvorak ⌘-C (physical "I" key) copies
+            // instead of focusing the Assistant input. RND-11340.
+            ignoreEventWhen: (e) => e.key.toLowerCase() !== 'i',
         }
     );
 
diff --git a/packages/gitbook/src/components/Search/SearchContainer.tsx b/packages/gitbook/src/components/Search/SearchContainer.tsx
index 0e6911909..452eff295 100644
--- a/packages/gitbook/src/components/Search/SearchContainer.tsx
+++ b/packages/gitbook/src/components/Search/SearchContainer.tsx
@@ -69,6 +69,10 @@ export function SearchContainer({
         },
         {
             enableOnFormTags: true,
+            // Match the logical character typed, not the physical key position, so
+            // non-QWERTY layouts don't trigger the shortcut by position (e.g. on
+            // Dvorak the physical "K"/"I" keys produce other characters). RND-11340.
+            ignoreEventWhen: (e) => e.key.toLowerCase() !== 'k',
         }
     );
 
@@ -84,6 +88,9 @@ export function SearchContainer({
         },
         {
             enableOnFormTags: true,
+            // Match the logical character so Dvorak ⌘-C (physical "I" key) copies
+            // instead of opening the Assistant. RND-11340.
+            ignoreEventWhen: (e) => e.key.toLowerCase() !== 'i',
         }
     );